CSRP3 antibody

Catalog No. ABIN6291316

Product Details anti-CSRP3 Antibody

Target: CSRP3 (Cysteine and Glycine-Rich Protein 3 (CSRP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSRP3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human CSRP3

Isotype: IgG

Application Details

Application Notes: IF 1:50 - 1:200

Comment:

Cardiac and slow-twitch skeletal muscles, Isoform 2 is expressed in striated muscle, Isoform 2 is specifically expressed at higher levels in patients with neuromuscular diseases, such as limb-girdle muscular dystrophy 2A (LGMD2A), Duchenne muscular dystrophy (DMD) and dermatomyositis

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CSRP3

Target: CSRP3 (Cysteine and Glycine-Rich Protein 3 (CSRP3))

Alternative Name: CSRP3 (CSRP3 Products)

Synonyms: CLP antibody, CMD1M antibody, CMH12 antibody, CRP3 antibody, LMO4 antibody, MLP antibody, MMLP antibody, csrp3 antibody, zgc:103468 antibody, CSRP3 antibody, csrp3-a antibody, cysteine and glycine rich protein 3 antibody, cysteine and glycine-rich protein 3 antibody, cysteine and glycine-rich protein 3 (cardiac LIM protein) antibody, cysteine and glycine rich protein 3 L homeolog antibody, CSRP3 antibody, Csrp3 antibody, csrp3 antibody, csrp3.L antibody

Background: This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Molecular Weight: 20.969 kDa

Gene ID: 8048

UniProt: P50461