LZTS2 antibody

Catalog No. ABIN6291682

Product Details anti-LZTS2 Antibody

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTS2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human LZTS2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for LZTS2

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Alternative Name: LZTS2 (LZTS2 Products)

Synonyms: lapser1 antibody, MGC89253 antibody, si:dkey-250a11.1 antibody, LAPSER1 antibody, BC014695 antibody, mKIAA1813 antibody, Lapser1 antibody, leucine zipper, putative tumor suppressor 2 antibody, leucine zipper tumor suppressor 2 antibody, leucine zipper, putative tumor suppressor 2a antibody, leucine zipper, putative tumor suppressor 2 S homeolog antibody, lzts2 antibody, LZTS2 antibody, lzts2a antibody, Lzts2 antibody, lzts2.S antibody

Background: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 72.759 kDa

Gene ID: 84445

UniProt: Q9BRK4