XMAP4 antibody, mtap4 antibody, AA407148 antibody, MAP-4 antibody, Mtap-4 antibody, Mtap4 antibody, microtubule associated protein 4 antibody, microtubule associated protein 4 L homeolog antibody, microtubule-associated protein 4 antibody, MAP4 antibody, map4.L antibody, Map4 antibody
Background
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene.