PDGFC antibody

Catalog No. ABIN6292249

Product Details anti-PDGFC Antibody

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFC antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PDGFC

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Expressed in the fallopian tube, vascular smooth muscle cells in kidney, breast and colon and in visceral smooth muscle of the gastrointestinal tract, Highly expressed in retinal pigment epithelia, Expressed in medulloblastoma, In the kidney, constitutively expressed in parietal epithelial cells of Bowman's capsule, tubular epithelial cells and in arterial endothelial cells (at protein level), Highly expressed in the platelets, prostate, testis and uterus, Higher expression is observed in uterine leiomyomata, Weaker expression in the spleen, thymus, heart, pancreas, liver, ovary cells and small intestine, and negligible expression in the colon and peripheral blood leukocytes

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for PDGFC

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Alternative Name: PDGFC (PDGFC Products)

Synonyms: SCDGF antibody, FALLOTEIN antibody, 1110064L01Rik antibody, AI647969 antibody, PDGF-C antibody, platelet derived growth factor C antibody, platelet-derived growth factor, C polypeptide antibody, PDGFC antibody, Pdgfc antibody

Target Type: Viral Protein

Background: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 39.029 kDa

Gene ID: 56034

UniProt: Q9NRA1

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling