HERPUD1 antibody
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- Target See all HERPUD1 Antibodies
- HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HERPUD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human HERPUD1
- Isotype
- IgG
- Top Product
- Discover our top product HERPUD1 Primary Antibody
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- Application Notes
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - Comment
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Widely expressed
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- HERPUD1 (Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1 (HERPUD1))
- Alternative Name
- HERPUD1 (HERPUD1 Products)
- Synonyms
- herpud1-a antibody, herp antibody, herpud1 antibody, mif1 antibody, sup antibody, HERPUD1 antibody, zgc:114134 antibody, HERP antibody, Mif1 antibody, SUP antibody, Herp antibody, Mifl antibody, Sup antibody, homocysteine inducible ER protein with ubiquitin like domain 1 S homeolog antibody, homocysteine inducible ER protein with ubiquitin like domain 1 L homeolog antibody, homocysteine inducible ER protein with ubiquitin like domain 1 antibody, homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 antibody, herpud1.S antibody, herpud1.L antibody, herpud1 antibody, HERPUD1 antibody, Herpud1 antibody
- Background
- The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined.
- Molecular Weight
- 43.72 kDa
- Gene ID
- 9709
- UniProt
- Q15011
- Pathways
- ER-Nucleus Signaling
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