Galectin 10 antibody

Catalog No. ABIN6292448

Product Details anti-Galectin 10 Antibody

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 10 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CLC

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Expressed abundantly in the bone marrow, Expressed exclusively by eosinophils and basophils, Not detected in monocytes and neutrophils, Expressed in CD25-positive regulatory T-cells (Treg) (at protein level), Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level), Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for Galectin 10

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Alternative Name: CLC (CLC Products)

Synonyms: GAL10 antibody, Gal-10 antibody, LGALS10 antibody, LGALS10A antibody, LPPL_HUMAN antibody, Clcp antibody, gal-10 antibody, Bsf3 antibody, CLC antibody, GAL 10 antibody, Gal-8 antibody, Gal8 antibody, Charcot-Leyden crystal galectin antibody, Charcot-Leyden crystal protein antibody, cardiotrophin-like cytokine factor 1 antibody, avian beta-defensin 10 antibody, CLC antibody, Clc antibody, Clcf1 antibody, AvBD10 antibody

Background: Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

Molecular Weight: 16.453 kDa

Gene ID: 1178

UniProt: Q05315

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response