LTC4S antibody

Catalog No. ABIN6293059

Product Details anti-LTC4S Antibody

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTC4S antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human LTC4S

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Detected in lung, platelets and the myelogenous leukemia cell line KG-1 (at protein level), LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells and platelets

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for LTC4S

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Alternative Name: LTC4S (LTC4S Products)

Synonyms: LTC4S antibody, ltc4s antibody, si:dkey-33h4.2 antibody, leukotriene C4 synthase antibody, leukotriene C4 synthase-like antibody, leukotriene C4 synthase, gene 1 antibody, Ltc4s antibody, LTC4S antibody, LTC4SL antibody, ltc4s.1 antibody, ltc4s antibody

Background: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum.

Molecular Weight: 16.567 kDa

Gene ID: 4056

UniProt: Q16873

Pathways: Cellular Response to Molecule of Bacterial Origin