MKL1 antibody
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- Target See all MKL1 Antibodies
- MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MKL1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human MKL1
- Isotype
- IgG
- Top Product
- Discover our top product MKL1 Primary Antibody
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- Application Notes
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - Comment
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Ubiquitously expressed, has been detected in lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, muscle, heart and brain
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))
- Alternative Name
- MKL1 (MKL1 Products)
- Synonyms
- MKL1 antibody, BSAC antibody, MAL antibody, MRTF-A antibody, Mrtf-a antibody, mrtf-a antibody, mrtfa antibody, AI852829 antibody, AMKL antibody, AW743281 antibody, AW821984 antibody, Bsac antibody, Mal antibody, Mrtf-A antibody, megakaryoblastic leukemia (translocation) 1 antibody, megakaryoblastic leukemia 1 protein antibody, megakaryoblastic leukemia (translocation) 1 S homeolog antibody, MKL (megakaryoblastic leukemia)/myocardin-like 1 antibody, MKL1 antibody, mkl1 antibody, Mkl1 antibody, mkl1.S antibody
- Background
- The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 98.919 kDa
- Gene ID
- 57591
- UniProt
- Q969V6
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