GP6 antibody

Catalog No. ABIN6293681

Product Details anti-GP6 Antibody

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of human GP6

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Megakaryocytes and platelets

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for GP6

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Alternative Name: GP6 (GP6 Products)

Synonyms: BDPLT11 antibody, GPIV antibody, GPVI antibody, 9830166G18Rik antibody, Gm469 antibody, Gpvi antibody, GP6 antibody, glycoprotein VI platelet antibody, glycoprotein 6 (platelet) antibody, glycoprotein VI antibody, platelet glycoprotein VI antibody, GP6 antibody, Gp6 antibody, LOC103346235 antibody

Background: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 36.866 kDa

Gene ID: 51206

UniProt: Q9HCN6