WDR35 antibody

Catalog No. ABIN6293806

Product Details anti-WDR35 Antibody

Target: WDR35 (WD Repeat Domain 35 (WDR35))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR35 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human WDR35

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for WDR35

Target: WDR35 (WD Repeat Domain 35 (WDR35))

Alternative Name: WDR35 (WDR35 Products)

Synonyms: 4930459M12Rik antibody, 4931430C06 antibody, mKIAA1336 antibody, RGD1564116 antibody, Wdr35 antibody, CED2 antibody, IFT121 antibody, im:7159945 antibody, si:ch211-206k20.4 antibody, WD repeat domain 35 antibody, Wdr35 antibody, WDR35 antibody, wdr35 antibody

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.

Molecular Weight: 133.547 kDa

Gene ID: 57539

UniProt: Q9P2L0

Pathways: Hedgehog Signaling