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ATP7A antibody
ATP7A
Reactivity: Human, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ATP7A Antibody
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Target
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ATP7A
(ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
Reactivity
All reactivities for ATP7A antibodies
Human, Dog
Host
All hosts for ATP7A antibodies
Rabbit
Clonality
All clonalities for ATP7A antibodies
Polyclonal
Conjugate
All conjugates for ATP7A antibodies
This ATP7A antibody is un-conjugated
Application
All applications for ATP7A antibodies
Western Blotting (WB)
Purification
Purified
Immunogen
ATP7 A antibody was raised using a synthetic peptide corresponding to a region with amino acids MKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYQ
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Alternatives
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Application Details
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Application Notes
WB: 2.5 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Lyophilized
Reconstitution
Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ATP0 antibody in PBS
Concentration
Lot specific
Buffer
PBS
Handling Advice
Avoid repeated freeze/thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
Target Details for ATP7A
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Target
ATP7A
(ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
Alternative Name
ATP7A (ATP7A Products )
Synonyms
ATP7A antibody, cal antibody, wu:fc43e01 antibody, zgc:153422 antibody, zgc:158633 antibody, DDBDRAFT_0218568 antibody, DDBDRAFT_0235190 antibody, DDB_0218568 antibody, DDB_0235190 antibody, atpase antibody, Atp7a antibody, kal antibody, atp7a antibody, DSMAX antibody, MK antibody, MNK antibody, SMAX3 antibody, Blo antibody, DXHXS1608e antibody, I14 antibody, Mo antibody, blotchy antibody, br antibody, brindled antibody, mottled antibody, Mnk antibody, ATPase copper transporting alpha antibody, ATPase, Cu++ transporting, alpha polypeptide antibody, P-type ATPase antibody, ATP synthase subunit a antibody, copper-transporting ATPase 1 antibody, ATP7A antibody, atp7a antibody, LOC100049514 antibody, Atp7a antibody, LOC412379 antibody
Background
The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene.
Molecular Weight
30 kDa (MW of target protein)
Pathways
Transition Metal Ion Homeostasis , Ribonucleoside Biosynthetic Process
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