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BACE2 antibody (Middle Region)

BACE2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN635132
  • Target See all BACE2 Antibodies
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 44
    • 33
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 2
    • 1
    Rabbit
    Clonality
    • 65
    • 1
    Polyclonal
    Conjugate
    • 30
    • 10
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BACE2 antibody is un-conjugated
    Application
    • 47
    • 31
    • 20
    • 13
    • 13
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Specificity
    BACE2 antibody was raised against the middle region of BACE2
    Purification
    Affinity purified
    Immunogen
    BACE2 antibody was raised using the middle region of BACE2 corresponding to a region with amino acids SLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGF
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    Discover our top product BACE2 Primary Antibody
  • Application Notes
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    BACE2 Blocking Peptide, catalog no. 33R-8612, is also available for use as a blocking control in assays to test for specificity of this BACE2 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of BACE2 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Alternative Name
    BACE2 (BACE2 Products)
    Synonyms
    AEPLC antibody, ALP56 antibody, ASP1 antibody, ASP21 antibody, BAE2 antibody, CEAP1 antibody, DRAP antibody, 1110059C24Rik antibody, AI850424 antibody, ARP1 antibody, CDA13 antibody, beta-site APP-cleaving enzyme 2 antibody, BACE2 antibody, Bace2 antibody
    Background
    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
    Molecular Weight
    37 kDa (MW of target protein)
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