RFXANK antibody (AA 18-31)

Catalog No. ABIN636183

Product Details anti-RFXANK Antibody

Target: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Binding Specificity: AA 18-31

Reactivity: Mammalian

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFXANK antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity chromatography purified

Immunogen: RFXB antibody was raised in rabbit using AA 18-31 [ASELGDPEDPGEEAC] of the RFX-B protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for RFXANK

Target: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Alternative Name: RFXB (RFXANK Products)

Synonyms: ANKRA1 antibody, BLS antibody, F14150_1 antibody, RFX-B antibody, Tvl1 antibody, regulatory factor X associated ankyrin containing protein antibody, regulatory factor X-associated ankyrin-containing protein antibody, RFXANK antibody, Rfxank antibody

Background: RFX-B is the gene responsible for the bare lymphocyte syndrome (BLS) which is characterized by a lack of MHC class II transcription. Subsequently, there is a lack of B and T cell responses to foreign antigens. RFX-B is a MHC class II transcription factor that is defective in BLS.