OPRK1 antibody (AA 366-380)

Catalog No. ABIN636321

Product Details anti-OPRK1 Antibody

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Binding Specificity: AA 366-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRK1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity chromatography purified

Immunogen: KOR antibody was raised in rabbit using AA 366-380 DPAYLRDIDGMNLPV of the human KOR-1 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for OPRK1

Target: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Alternative Name: KOR (OPRK1 Products)

Synonyms: OPRK1 antibody, LOC780448 antibody, kor antibody, KOR antibody, OPRK antibody, K-OR-1 antibody, KOR-1 antibody, MSL-1 antibody, Oprk2 antibody, R21 antibody, opioid receptor, kappa 1 antibody, opioid receptor kappa 1 antibody, oprk1 antibody, OPRK1 antibody, Oprk1 antibody

Background: The mu, delta, and kappa opioid receptors are G protein-coupled receptors (GPCRs) of the nervous system, which control pain, stress, and addictive behaviors. The kappa opioid receptor (KOR-1) plays a role in arousal and regulation of autonomic and neuroendocrine functions and is the receptor for dynorphins. KOR-1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.