NPX1 antibody

Catalog No. ABIN636573

Product Details anti-NPX1 Antibody

Target: NPX1 (Neuronal Pentraxin 1 (NPX1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NPX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogen: NP1 antibody was raised in goat using highly pure recombinant human NP-1 as the immunogen.

Application Details

Application Notes: ELISA: 0.5-2 µg/mL, Inhibition: 0.4-0.6 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for NPX1

Target: NPX1 (Neuronal Pentraxin 1 (NPX1))

Alternative Name: NP1 (NPX1 Products)

Synonyms: NP1 antibody, D11Bwg1004e antibody, Np1 antibody, np1 antibody, nptx1 antibody, neuronal pentraxin 1 antibody, neuronal pentraxin 1 L homeolog antibody, Nptx1 antibody, NPTX1 antibody, nptx1 antibody, nptx1.L antibody

Background: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds.

Molecular Weight: 3.4 kDa (predicted detection band MW)

Pathways: Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interactome