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CYP11B2 antibody (AA 120-147)
CYP11B2
Reactivity: Human, Mouse
WB, IHC (p), FACS
Host: Rabbit
Polyclonal
RB16930
unconjugated
Product Details anti-CYP11B2 Antibody
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Target
See all CYP11B2 Antibodies
CYP11B2
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
Binding Specificity
All epitopes for CYP11B2 antibodies
AA 120-147
Reactivity
All reactivities for CYP11B2 antibodies
Human, Mouse
Host
All hosts for CYP11B2 antibodies
Rabbit
Clonality
All clonalities for CYP11B2 antibodies
Polyclonal
Conjugate
All conjugates for CYP11B2 antibodies
This CYP11B2 antibody is un-conjugated
Application
All applications for CYP11B2 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CYP11B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-147 amino acids from the Central region of human CYP11B2.
Clone
RB16930
Isotype
Ig Fraction
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Discover our top product CYP11B2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for CYP11B2
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Target
CYP11B2
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
Alternative Name
CYP11B2 (CYP11B2 Products )
Synonyms
ALDOS antibody, CPN2 antibody, CYP11B antibody, CYP11BL antibody, CYPXIB2 antibody, P-450C18 antibody, P450C18 antibody, P450aldo antibody, Cpn2 antibody, Cyp11b antibody, Cyp11b-2 antibody, Cp45as antibody, Cyp11b3 antibody, RNCP45AS antibody, cytochrome P450 family 11 subfamily B member 2 antibody, cytochrome P450, family 11, subfamily b, polypeptide 2 antibody, aldosterone synthase antibody, cytochrome P450, family 11, subfamily B, polypeptide 2 antibody, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 antibody, CYP11B2 antibody, Cyp11b2 antibody
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
Molecular Weight
57560
Gene ID
1585
NCBI Accession
NP_000489
UniProt
P19099
Pathways
ACE Inhibitor Pathway , Metabolism of Steroid Hormones and Vitamin D , Steroid Hormone Biosynthesis , Regulation of Systemic Arterial Blood Pressure by Hormones , C21-Steroid Hormone Metabolic Process , Feeding Behaviour
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