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TGIF1 antibody (AA 208-237)

TGIF1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB14110 unconjugated
Catalog No. ABIN655999
  • Target See all TGIF1 Antibodies
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Binding Specificity
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-237
    Reactivity
    • 48
    • 13
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 41
    • 6
    • 1
    Rabbit
    Clonality
    • 43
    • 5
    Polyclonal
    Conjugate
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TGIF1 antibody is un-conjugated
    Application
    • 33
    • 27
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    C
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This TGIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF1.
    Clone
    RB14110
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TGIF1 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Alternative Name
    TGIF1 (TGIF1 Products)
    Synonyms
    HPE4 antibody, TGIF antibody, AA959811 antibody, AI462167 antibody, Tgif antibody, Tfig antibody, fa06h05 antibody, fb33g11 antibody, zgc:55852 antibody, wu:fa06h05 antibody, wu:fb33g11 antibody, hpe4 antibody, tgif antibody, tgif1 antibody, TGFB induced factor homeobox 1 antibody, TGFB-induced factor homeobox 1 antibody, TGFB induced factor homeobox 1 S homeolog antibody, TGIF1 antibody, Tgif1 antibody, tgif1 antibody, tgif1.S antibody
    Background
    The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.
    Molecular Weight
    43013
    Gene ID
    7050
    NCBI Accession
    NP_001265611, NP_001265613, NP_001265615, NP_003235, NP_733796, NP_775299, NP_775300, NP_775301, NP_775302, NP_775303, NP_777480
    UniProt
    Q15583
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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