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TMEM43 antibody (AA 195-223)

TMEM43 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB32139 unconjugated
Catalog No. ABIN656549
  • Target See all TMEM43 Antibodies
    TMEM43 (Transmembrane Protein 43 (TMEM43))
    Binding Specificity
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    AA 195-223
    Reactivity
    • 21
    • 2
    Human
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    This TMEM43 antibody is un-conjugated
    Application
    • 18
    • 16
    • 16
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.
    Clone
    RB32139
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TMEM43 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    TMEM43 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    TMEM43 (Transmembrane Protein 43 (TMEM43))
    Alternative Name
    TMEM43 (TMEM43 Products)
    Synonyms
    zgc:85946 antibody, ARVC5 antibody, ARVD5 antibody, EDMD7 antibody, LUMA antibody, 1200015A22Rik antibody, transmembrane protein 43 antibody, TMEM43 antibody, tmem43 antibody, Tmem43 antibody
    Background
    This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
    Molecular Weight
    44876
    Gene ID
    79188
    NCBI Accession
    NP_077310
    UniProt
    Q9BTV4
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