MMP7 antibody (Matrix Metallopeptidase 7 (Matrilysin, Uterine))

Details for Product anti-MMP7 Antibody No. ABIN6566649
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
189
95
64
8
5
4
2
2
1
1
Host
Rabbit
177
37
9
Clonality
Polyclonal
Conjugate
This MMP7 antibody is un-conjugated
14
12
10
4
4
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
167
102
85
44
18
17
13
11
10
9
3
3
2
1
1
1
1
1
1
Options
Immunogen Recombinant protein of human MMP7
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name MMP7 (MMP7 Antibody Abstract)
Background

Synonyms: Matrilysin,Matrin,Matrix Metalloproteinase 7,Matrix metalloproteinase-7,MMP 7,MMP-7,MMP7,MMP7,MPSL1,PUMP 1,Pump 1 protease,Pump-1 protease,PUMP1,Uterine matrilysin,Uterine metalloproteinase

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.

Molecular Weight

Observed_MW: 30kDa

Calculated_MW: 29kDa

Gene ID 4316
UniProt P09237
Pathways Production of Molecular Mediator of Immune Response
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) antibody (ABIN6566649) Immunohistochemistry of paraffin-embedded human colon carcinoma using MMP7 antibody.
Image no. 2 for anti-Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) antibody (ABIN6566649) Western blot analysis of extracts of HT-29 cells, using MMP7 antibody.