RAP1A antibody
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- Target See all RAP1A Antibodies
- RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RAP1A antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human RAP1A (NP_002875.1).
- Isotype
- IgG
- Top Product
- Discover our top product RAP1A Primary Antibody
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- Application Notes
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
- Alternative Name
- RAP1A (RAP1A Products)
- Synonyms
- KREV-1 antibody, KREV1 antibody, RAP1 antibody, SMGP21 antibody, AI848598 antibody, G-22K antibody, Krev-1 antibody, Rap1 antibody, RAP-1A antibody, rap 1A antibody, wu:fc66g06 antibody, zgc:86676 antibody, krev-1 antibody, krev1 antibody, rap1 antibody, RAP1A, member of RAS oncogene family antibody, RAS-related protein 1a antibody, RAP1A, member of RAS oncogene family a antibody, RAP1A, member of RAS oncogene family L homeolog antibody, RAP1A antibody, Rap1a antibody, rap1aa antibody, rap1a.L antibody
- Background
- This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 21kDa
Calculated_MW: 20kDa
- Gene ID
- 5906
- UniProt
- P62834
- Pathways
- TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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