SLC12A1 antibody
-
- Target See all SLC12A1 Antibodies
- SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SLC12A1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human SLC12A1
- Isotype
- IgG
- Top Product
- Discover our top product SLC12A1 Primary Antibody
-
-
- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
- Alternative Name
- SLC12A1 (SLC12A1 Products)
- Synonyms
- slc12a1 antibody, SLC12A1 antibody, DKFZp469A2020 antibody, BSC1 antibody, NKCC2 antibody, Nkcc2 antibody, AI788571 antibody, D630042G03Rik antibody, mBSC1 antibody, urehr3 antibody, si:ch211-220f12.1 antibody, solute carrier family 12 member 1 antibody, solute carrier family 12, member 1 antibody, si:ch211-220f12.1 antibody, SLC12A1 antibody, Slc12a1 antibody
- Background
-
Synonyms: BSC1,Bumetanide sensitive sodium 3,Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2,Kidney specific Na K Cl symporter,Kidney-specific Na-K-Cl symporter,MGC48843,Na K 2Cl cotransporter,NKCC2,potassiumchloride cotransporter 2,S12A1,Slc12a1,sodium potassium chloride cotransporter 2,solute carrier family 12 (sodium/potassium/chloride transporters),Solute carrier family 12 member 1
Background: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.
- Molecular Weight
-
Observed_MW: 150kDa
Calculated_MW: 121kDa
- Gene ID
- 6557
- UniProt
- Q13621
-