NDC80 antibody

Catalog No. ABIN6568271

Product Details anti-NDC80 Antibody

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDC80 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human NDC80

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDC80

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Alternative Name: NDC80 (NDC80 Products)

Synonyms: CG9938 antibody, Dmel\\CG9938 antibody, Hec1 antibody, NDC80 antibody, dNdc80 antibody, dmNdc80 antibody, hec1 antibody, KNTC2 antibody, ndc10 antibody, tid3 antibody, 2610020P18Rik antibody, AV139730 antibody, HEC antibody, HEC1 antibody, Kntc2 antibody, kntc2l antibody, wu:fb52e02 antibody, zgc:111801 antibody, HsHec1 antibody, TID3 antibody, hsNDC80 antibody, kntc2 antibody, NDC80, kinetochore complex component antibody, CG9938 gene product from transcript CG9938-RA antibody, spindle pole body protein Ndc80 antibody, kinetochore protein Ndc80 antibody, NDC80 homolog, kinetochore complex component (S. cerevisiae) antibody, NDC80 kinetochore complex component antibody, NDC80 kinetochore complex component S homeolog antibody, NDC80 antibody, Ndc80 antibody, ndc80 antibody, ndc80.S antibody

Background:

Synonyms: from Entrez Gene ,HEC,Highly expressed in cancer,Highly expressed in cancer protein,Highly expressed in cancer rich in leucine heptad repeats,HsHec1,hsNDC80,Kinetochore associated 2,Kinetochore associated protein 2,Kinetochore protein Hec1,Kinetochore protein NDC80 homolog,Kinetochore-associated protein 2,KNTC2,ndc80,NDC80 homolog kinetochore complex component,NDC80 kinetochore complex component homolog,NDC80,S. cerevisiae,homolog of,NDC80,Retinoblastoma associated protein HEC,Retinoblastoma-associated protein HEC,TID3

Background: This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

Molecular Weight:

Observed_MW: 74kDa

Calculated_MW: 73kDa

Gene ID: 10403

UniProt: O14777

Pathways: Maintenance of Protein Location