CBFA2T3 antibody
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- Target See all CBFA2T3 Antibodies
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CBFA2T3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human CBFA2T3
- Isotype
- IgG
- Top Product
- Discover our top product CBFA2T3 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
- Alternative Name
- CBFA2T3 (CBFA2T3 Products)
- Synonyms
- A630044F12Rik antibody, AI465270 antibody, AW229127 antibody, Cbfa2t3h antibody, ETO-2 antibody, Eto2 antibody, MTGR2 antibody, MTG16a antibody, MTG16b antibody, ETO2 antibody, MTG16 antibody, ZMYND4 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) antibody, CBFA2/RUNX1 translocation partner 3 antibody, Cbfa2t3 antibody, CBFA2T3 antibody
- Background
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Synonyms: Cbfa2t3,Ccore binding factor runt domain alpha subunit 2 translocated to 3,ETO2,hMTG16,hMTG16a,hMTG16b,MTG16,MTG16,MTG8 related gene 2,MTG8 related protein MTG16a,MTG8 related protein MTG16b,MTG8-related protein 2,MTGR2,Myeloid translocation gene 8 and 16b,Myeloid translocation gene on chromosome 16 protein,Protein CBFA2T3,Zinc finger MYND domain-containing protein 4,ZMYND4
Background: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16,21)(q24,q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
- Molecular Weight
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Observed_MW: 60kDa
Calculated_MW: 7kDa/62kDa/63kDa/71kDa
- Gene ID
- 863
- UniProt
- O75081
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