UNC5B antibody

Catalog No. ABIN6568539

Product Details anti-UNC5B Antibody

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human UNC5B

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UNC5B

Target: UNC5B (Netrin receptor UNC5B (UNC5B))

Alternative Name: UNC5B (UNC5B Products)

Synonyms: unc5h2 antibody, 6330415E02Rik antibody, A630020F16 antibody, D10Bwg0792e antibody, Unc5h2 antibody, UNC5H2 antibody, p53RDL1 antibody, UNC5C antibody, UNC5B antibody, p53rdl1 antibody, unc-5 netrin receptor B antibody, unc-5 netrin receptor B L homeolog antibody, unc5b antibody, Unc5b antibody, UNC5B antibody, unc5b.L antibody

Background:

Synonyms: 6330415E02Rik,A630020F16,D10Bwg0792e ,Netrin receptor UNC5B,Netrin receptor UNC5B Precursor,p53 regulated receptor for death and life,p53 regulated receptor for death and life protein 1 ,p53-regulated receptor for death and life protein 1,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,Protein XUNC 5 ,Transmembrane receptor Unc5H2,Unc 5 homolog 2,Unc 5 homolog B,Unc 5 netrin receptor B,UNC 5B,Unc5 (C.elegans homolog) b,Unc5b,UNC5B,UNC5H2

Background: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

Molecular Weight:

Observed_MW: 104kDa

Calculated_MW: 102kDa/103kDa

Gene ID: 219699

UniProt: Q8IZJ1