PDCD10 antibody

Catalog No. ABIN6568687

Product Details anti-PDCD10 Antibody

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD10 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PDCD10

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDCD10

Target: PDCD10 (Programmed Cell Death 10 (PDCD10))

Alternative Name: PDCD10 (PDCD10 Products)

Synonyms: CCM3 antibody, TFAR15 antibody, 2410003B13Rik antibody, Ccm3 antibody, Tfa15 antibody, Tfar15 antibody, zgc:85629 antibody, ccm3a antibody, pdcd10 antibody, zgc:65826 antibody, programmed cell death 10 antibody, programmed cell death 10 S homeolog antibody, programmed cell death 10b antibody, programmed cell death 10a antibody, PDCD10 antibody, Pdcd10 antibody, pdcd10.S antibody, pdcd10b antibody, pdcd10a antibody

Background:

Synonyms: Apoptosis related protein 15,CCM3,Cerebral cavernous malformations 3 protein,MGC1212,MGC24477,PDC10,PDCD 10,PDCD10,Programmed cell death 10,Programmed cell death protein 10,TF 1 cell apoptosis related protein 15,TF-1 cell apoptosis-related protein 15,TFAR15

Background: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight:

Observed_MW: 26kDa

Calculated_MW: 24kDa

Gene ID: 11235

UniProt: Q9BUL8