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PAICS antibody (N-Term)
PAICS
Reactivity: Human, Mouse
WB, FACS, IHC (p)
Host: Rabbit
Polyclonal
RB31339
unconjugated
Product Details anti-PAICS Antibody
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Target
See all PAICS Antibodies
PAICS
(phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
Binding Specificity
All epitopes for PAICS antibodies
AA 95-123, N-Term
Reactivity
All reactivities for PAICS antibodies
Human, Mouse
Host
All hosts for PAICS antibodies
Rabbit
Clonality
All clonalities for PAICS antibodies
Polyclonal
Conjugate
All conjugates for PAICS antibodies
This PAICS antibody is un-conjugated
Application
All applications for PAICS antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
C
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PAICS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human PAICS.
Clone
RB31339
Isotype
Ig Fraction
Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
PAICS Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Target Details for PAICS
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Target
PAICS
(phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
Alternative Name
PAICS (PAICS Products )
Synonyms
cb293 antibody, sb:cb293 antibody, wu:fa28a05 antibody, GB14262 antibody, DDBDRAFT_0218550 antibody, DDBDRAFT_0230088 antibody, DDB_0218550 antibody, DDB_0230088 antibody, AIRC antibody, AS antibody, ADE2 antibody, ADE2H1 antibody, PAIS antibody, Ade2h1 antibody, Airc antibody, ade2 antibody, airc antibody, paics antibody, pais antibody, 2610511I09Rik antibody, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antibody, multifunctional protein ADE2 antibody, phosphoribosylaminoimidazole carboxylase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase antibody, PAICS antibody, paics antibody, LOC551966 antibody, Tsp_02239a antibody, Tsp_02239 antibody, CNE02500 antibody, purC/E antibody, Paics antibody, paics.2.L antibody
Background
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight
47079
Gene ID
10606
NCBI Accession
NP_001072992 , NP_001072993 , NP_006443
UniProt
P22234
Pathways
Chromatin Binding
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