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PAICS antibody (N-Term)

PAICS Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB31339 unconjugated
Catalog No. ABIN656869
  • Target See all PAICS Antibodies
    PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
    Binding Specificity
    • 15
    • 9
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    AA 95-123, N-Term
    Reactivity
    • 62
    • 23
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 57
    • 5
    Rabbit
    Clonality
    • 57
    • 5
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAICS antibody is un-conjugated
    Application
    • 34
    • 20
    • 20
    • 17
    • 13
    • 13
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    C
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PAICS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the N-terminal region of human PAICS.
    Clone
    RB31339
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    PAICS Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
    Alternative Name
    PAICS (PAICS Products)
    Synonyms
    cb293 antibody, sb:cb293 antibody, wu:fa28a05 antibody, GB14262 antibody, DDBDRAFT_0218550 antibody, DDBDRAFT_0230088 antibody, DDB_0218550 antibody, DDB_0230088 antibody, AIRC antibody, AS antibody, ADE2 antibody, ADE2H1 antibody, PAIS antibody, Ade2h1 antibody, Airc antibody, ade2 antibody, airc antibody, paics antibody, pais antibody, 2610511I09Rik antibody, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antibody, multifunctional protein ADE2 antibody, phosphoribosylaminoimidazole carboxylase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase antibody, PAICS antibody, paics antibody, LOC551966 antibody, Tsp_02239a antibody, Tsp_02239 antibody, CNE02500 antibody, purC/E antibody, Paics antibody, paics.2.L antibody
    Background
    This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    47079
    Gene ID
    10606
    NCBI Accession
    NP_001072992, NP_001072993, NP_006443
    UniProt
    P22234
    Pathways
    Chromatin Binding
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