LONP1 antibody
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- Target See all LONP1 Antibodies
- LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LONP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human LONP1
- Isotype
- IgG
- Top Product
- Discover our top product LONP1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))
- Alternative Name
- LONP1 (LONP1 Products)
- Synonyms
- PRSS15 antibody, prss15 antibody, fc64d11 antibody, wu:fc64d11 antibody, LON antibody, LONP antibody, LonHS antibody, PIM1 antibody, hLON antibody, 1200017E13Rik antibody, Prss15 antibody, Lon antibody, lon peptidase 1, mitochondrial antibody, ATP-dependent Lon protease antibody, LONP1 antibody, lonp1 antibody, Lonp1 antibody, PIM1 antibody
- Background
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Synonyms: hLON,hLON ATP dependent protease,LON,lon peptidase 1,mitochondrial,LON protease,Lon protease homolog,Lon protease like protein,Lon protease-like protein,LONHs,LONM,LONP,Lonp1,MGC1498,mitochondrial,Mitochondrial ATP dependent protease Lon,Mitochondrial ATP-dependent protease Lon,Mitochondrial lon peptidase 1,PIM1,Protease serine 15,PRSS15,Serine protease 15
Background: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
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Observed_MW: 105kDa
Calculated_MW: 85kDa/100kDa/106kDa
- Gene ID
- 9361
- UniProt
- P36776
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