C8orf4 antibody
-
- Target See all C8orf4 Antibodies
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This C8orf4 antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human C8orf4 (NP_064515.1).
- Isotype
- IgG
- Top Product
- Discover our top product C8orf4 Primary Antibody
-
-
- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
- Alternative Name
- C8orf4 (C8orf4 Products)
- Synonyms
- TC-1 antibody, TC1 antibody, 1110065B09Rik antibody, AW121743 antibody, AW321058 antibody, C8ORF4 antibody, transcriptional and immune response regulator antibody, chromosome 22 open reading frame, human C8orf4 antibody, TCIM antibody, C22H8ORF4 antibody, Tcim antibody
- Background
- This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
- Molecular Weight
-
Observed_MW: Refer to figures
Calculated_MW: 12kDa
- Gene ID
- 56892
- UniProt
- Q9NR00
-