Thimet Oligopeptidase 1 antibody

Catalog No. ABIN6571900

Product Details anti-Thimet Oligopeptidase 1 Antibody

Target: Thimet Oligopeptidase 1 (THOP1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thimet Oligopeptidase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human THOP1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Alternative Name: THOP1 (THOP1 Products)

Synonyms: EP24.15 antibody, MEPD_HUMAN antibody, MP78 antibody, TOP antibody, AI131655 antibody, AI327041 antibody, THOP1 antibody, thop1 antibody, MGC147297 antibody, LOC397806 antibody, mepd antibody, thimet oligopeptidase 1 antibody, thimet oligopeptidase 1 L homeolog antibody, thimet oligopeptidase antibody, peptidase antibody, Thimet oligopeptidase antibody, THOP1 antibody, Thop1 antibody, thop1 antibody, thop1.L antibody, Tc00.1047053506411.10 antibody, Tc00.1047053511237.10 antibody, Noca_4613 antibody, ANI_1_1400064 antibody, MBOO_RS10705 antibody, AOR_1_880174 antibody, AnaeK_0425 antibody, MPAL_RS03920 antibody, Hoch_5061 antibody, mepd antibody

Background:

Synonyms: EC 3.4.24.15,Endopeptidase 24.15,EP24.15 ,MEPD,MP78,Thimet oligopeptidase 1,Thimet oligopeptidase,Thop1,THOP1,TOP

Background: The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.

Molecular Weight:

Observed_MW: 79kDa

Calculated_MW: 28kDa/78kDa

Gene ID: 7064

UniProt: P52888