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CSF1R antibody
CSF1R
Reactivity: Human
WB
Host: Mouse
Monoclonal
177CT7-1-1
unconjugated
Product Details anti-CSF1R Antibody
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Target
See all CSF1R Antibodies
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Reactivity
All reactivities for CSF1R antibodies
Human
Host
All hosts for CSF1R antibodies
Mouse
Clonality
All clonalities for CSF1R antibodies
Monoclonal
Conjugate
All conjugates for CSF1R antibodies
This CSF1R antibody is un-conjugated
Application
All applications for CSF1R antibodies
Western Blotting (WB)
Purification
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Immunogen
This CSF1R Monoclonal antibody was raised using purified His-tagged recombinant human CSF1R.
Clone
177CT7-1-1
Isotype
IgG1, IgM kappa
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Alternatives
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Application Details
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Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for CSF1R
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Target
CSF1R
(Colony Stimulating Factor 1 Receptor (CSF1R))
Alternative Name
CSF1R (CSF1R Products )
Synonyms
AI323359 antibody, CD115 antibody, CSF-1R antibody, Csfmr antibody, Fim-2 antibody, Fms antibody, M-CSF-R antibody, M-CSFR antibody, C-FMS antibody, CSFR antibody, FIM2 antibody, FMS antibody, HDLS antibody, PDGFRB antibody, MGC89146 antibody, CSF-1-R antibody, c-fms antibody, mrfms antibody, CSF1 antibody, M-CSF antibody, csf1r antibody, fms antibody, panther antibody, colony stimulating factor 1 receptor antibody, macrophage colony-stimulating factor receptor antibody, colony stimulating factor 1 receptor, a antibody, Csf1r antibody, CSF1R antibody, m-csfr antibody, csf1r antibody, csf1ra antibody
Background
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq].
Molecular Weight
107984
Gene ID
1436
NCBI Accession
NP_005202
UniProt
P07333
Pathways
RTK Signaling , Inositol Metabolic Process , Cell-Cell Junction Organization
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