FNDC5 antibody (AA 32-143)

Catalog No. ABIN6654179

Product Details anti-FNDC5 Antibody

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Binding Specificity: AA 32-143

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNDC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: Human recombinant protein (amino acids D32-E143) was used as the immunogen for the FNDC5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FNDC5 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FNDC5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FNDC5

Target: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Alternative Name: FNDC5 (FNDC5 Products)

Synonyms: FRCP2 antibody, irisin antibody, 1500001L03Rik antibody, AI836596 antibody, C87088 antibody, PeP antibody, Pxp antibody, fndc5 antibody, si:dkey-264p5.1 antibody, zgc:158684 antibody, fibronectin type III domain containing 5 antibody, fibronectin type III domain containing 5b antibody, FNDC5 antibody, Fndc5 antibody, fndc5b antibody

Background: Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants.

UniProt: Q8NAU1

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation