SLC18A2 antibody (C-Term)

Catalog No. ABIN6658243

Product Details anti-SLC18A2 Antibody

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Binding Specificity: C-Term

Reactivity: Rat

Host: Sheep

Clonality: Polyclonal

Conjugate: This SLC18A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Cross reactivity expected with human, reactivity with Vesicular Monoamine Transporter 2 from other species has not been determined.

Purification: Anti-Vesicular Monoamine Transporter 2 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-Vesicular Monoamine Transporter 2 Antibody is directed against rat Vesicular Monoamine Transporter 2.

Immunogen:

Immunogen: Anti-Vesicular Monoamine Transporter 2 Antibody was produced in sheep by repeated immunizations with synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region conjugated to KLH.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-VMAT2 antibody is suitable for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 57 kDa in size corresponding to VMAT2 protein in Western Blot of rat caudate lysate.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Target Details for SLC18A2

Target: SLC18A2 (Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))

Alternative Name: Vesicular Monoamine Transporter 2 (VMAT2) (SLC18A2 Products)

Synonyms: 1110037L13Rik antibody, 9330105E13 antibody, VAT2 antibody, Vmat2 antibody, MNAT antibody, VMAT-2 antibody, VMAT2 antibody, solute carrier family 18 (vesicular monoamine), member 2 antibody, solute carrier family 18 member A2 antibody, Slc18a2 antibody

Background:

Synonyms: Synaptic vesicular amine transporter, Monoamine transporter, Solute carrier family 18 member 2, Vesicular amine transporter 2

Background: Vesicular Monoamine Transporter 2 antibody recognizes Vesicular neurotransmitter transporter which sequesters the transmitters into synaptic vesicles. The vesicular monoamine transporter 2 (VMAT2) is responsible for catecholamine and serotonin storage in central synapses. Antibodies specific for VMAT have been used to monitor expression of the transporter during development and in aging and can be effectively used as a marker for monoamine terminals.Therefore, VMAT2 antibody is ideal for investigators involved in Neuronal plasticity and, more generally in Neuroscience.

Gene Name: VMAT2

Gene ID: 6571

NCBI Accession: NP_003045

UniProt: Q05940