SLC9A3R1 antibody (AA 69-338)
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- Target See all SLC9A3R1 Antibodies
- SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))
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Binding Specificity
- AA 69-338
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC9A3R1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for EBP50/NHERF-1/SLC9A3R1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
- Rabbit IgG polyclonal antibody for EBP50/NHERF-1/SLC9A3R1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human EBP50/NHERF-1/SLC9A3R1 recombinant protein (Position: K69-R338).
- Isotype
- IgG
- Top Product
- Discover our top product SLC9A3R1 Primary Antibody
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- Application Notes
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Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL
- Comment
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))
- Alternative Name
- SLC9A3R1 (SLC9A3R1 Products)
- Synonyms
- EBP50 antibody, NHERF antibody, NHERF-1 antibody, NHERF1 antibody, NPHLOP2 antibody, SLC9A3R1 antibody, cb895 antibody, slc9a3r2 antibody, wu:fd20a02 antibody, zgc:55541 antibody, zgc:77629 antibody, EBP-50 antibody, NHE-RF antibody, nherf antibody, nherf-1 antibody, nherf1 antibody, slc9a3r1 antibody, SLC9A3 regulator 1 antibody, microRNA 3615 antibody, solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a antibody, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 antibody, SLC9A3 regulator 1 S homeolog antibody, SLC9A3R1 antibody, MIR3615 antibody, slc9a3r1a antibody, Slc9a3r1 antibody, slc9a3r1.S antibody
- Background
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Synonyms: Na(+)/H(+) exchange regulatory cofactor NHE-RF1, NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1, SLC9A3R1, NHERF, NHERF1
Background: Sodium-hydrogen antiporter 3 regulator 1 is a regulator of Sodium-hydrogen antiporter 3. It is encoded by the gene SLC9A3R1. It is mapped to 17q25.1. This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.
- Gene ID
- 9368
- UniProt
- O14745
- Pathways
- Proton Transport, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
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