CD2 antibody (CF®488A)

Catalog No. ABIN6934016

Product Details anti-CD2 Antibody (CF®488A)

Target: CD2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD2 antibody is conjugated to CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Purification: Purified by Protein A/G

Immunogen: Human CD2 protein

Clone: BH1

Isotype: IgG2b kappa

Application Details

Application Notes:

Positive Control: 293T or Jurkat cells. Lymph node and tonsil.

Known Application: Flow Cytometry: 5 µL per test per one million cells (or 5 µL per 100 µL of whole blood)Immunofluorescence (1:50-1:100)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CD2

Target: CD2

Alternative Name: CD2 / Lymphocyte Function Antigen 2 (LFA-2) (CD2 Products)

Synonyms: CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody

Background: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Molecular Weight: 50kDa

Gene ID: 914

UniProt: P06729