P-Cadherin antibody

Catalog No. ABIN6935416

Product Details anti-P-Cadherin Antibody

Target: P-Cadherin (CDH3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This P-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: Recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

Cross-Reactivity (Details): Human,

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human P-cadherin fusion protein

Clone: 12H6

Isotype: IgG1

Application Details

Application Notes:

Positive Control: A431 or PC-3 cells. Pancreas, Placenta or Prostate.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Expiry Date: 24 months

Target Details for P-Cadherin

Target: P-Cadherin (CDH3)

Alternative Name: CDH3 (CDH3 Products)

Synonyms: CDH3 antibody, Cadherin-3 antibody, AI385538 antibody, Cadp antibody, Cdhp antibody, P-cadherin antibody, Pcad antibody, CDHP antibody, HJMD antibody, PCAD antibody, E-Cad antibody, E-cadherin antibody, EP-cadherin antibody, XTCAD-1 antibody, c-cadherin antibody, cadherin-1 antibody, cdh1 antibody, cdh1-b antibody, cdh3 antibody, cdhc-A antibody, cdhp antibody, hjmd antibody, l-cam antibody, lcam antibody, pcad antibody, uvo antibody, uvomorulin antibody, xb-cad antibody, xcdh1 antibody, CDH15 antibody, K-CAM antibody, cadherin 3 antibody, cadherin 3 L homeolog antibody, Cadherin-3 antibody, CDH3 antibody, Cdh3 antibody, cdh3.L antibody, cdh-3 antibody

Background: Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin,P-Cadherin (CDH3)
Cellular localisation: Cell surface

Molecular Weight: 116kDa

Gene ID: 1001, 191842

UniProt: P22223