CSTA antibody (AA 1-98)

Catalog No. ABIN6937037

Product Details anti-CSTA Antibody

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Binding Specificity: AA 1-98

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTA antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human CSTA protein (around aa 1-98) (exact sequence is proprietary)

Clone: CSTA-2882

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Human tonsil or prostate tissue (IHC).

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for CSTA

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Alternative Name: CSTA (CSTA Products)

Synonyms: AREI antibody, STF1 antibody, STFA antibody, CST antibody, CSTA antibody, ATCYSA antibody, FL3-27 antibody, T20B5.8 antibody, T20B5_8 antibody, cystatin A antibody, cystatin A antibody, cystatin A1 antibody, cystatin-A antibody, CSTA antibody, Csta1 antibody, Csta antibody, CYSA antibody, LOC100725920 antibody

Background: STF1, STFA, AREI, cstA, Stefin A,Cystatin A
Cellular localisation: Cell Surface, Cytoplasmic and Nuclear.

Molecular Weight: 11kDa

Gene ID: 1475, 518198

UniProt: P01040

Pathways: Response to Water Deprivation