GNAQ antibody
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- Target See all GNAQ Antibodies
- GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GNAQ antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- Specificity
- GNAQis 359 amino acids long and is identical in all but 1 amino acid residue to the Mouse protein. Analysis of human genomic DNA revealed an intronless sequence with strong homology to human GNAQ cDNA. In comparison to GNAQ cDNA, this genomic DNA sequence included several small deletions and insertions that altered the reading frame, multiple single based changes, and a premature termination codon in the open reading frame, all hallmarks of a processed pseudogene. Probes derived from human GNAQ cDNA sequence mapped both chromosomes 2 and 9 in higher constringency genomic blot analyses of DNA from a panel of human/rodent hybrid cell lines.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human GNAQ protein
- Clone
- GNAQ-2434
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product GNAQ Primary Antibody
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- Application Notes
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Known_Application: ELISA (For coating, order Ab without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HL-60, MOLT-4 and MCF-7 cells. Predominantly expressed in ovary, prostate, testis and colon.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
- Alternative Name
- GNAQ (GNAQ Products)
- Synonyms
- si:ch73-270f14.2 antibody, CMC1 antibody, G-ALPHA-q antibody, GAQ antibody, SWS antibody, Galphaq antibody, Gnaq antibody, g-alpha-q antibody, gaq antibody, gnaqb antibody, 1110005L02Rik antibody, 6230401I02Rik antibody, AA408290 antibody, AW060788 antibody, Dsk1 antibody, Dsk10 antibody, Gq antibody, GqI antibody, guanine nucleotide binding protein (G protein), q polypeptide antibody, G protein subunit alpha q antibody, guanine nucleotide binding protein (G protein), q polypeptide S homeolog antibody, guanine nucleotide binding protein, alpha q polypeptide antibody, gnaq antibody, GNAQ antibody, Gnaq antibody, gnaq.S antibody
- Background
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CMC1, G alpha Q, G protein alpha Q, GAQ, guanine nucleotide binding protein (G protein), q polypeptide, Guanine nucleotide-binding protein G(q) subunit alpha, SWS,Guanine nucleotide-binding protein alpha-q / GNAQ / G-ALPHA-q
Cellular localisation: Cytoplasmic and Cell Surface - Molecular Weight
- 45kDa
- Gene ID
- 2776, 269782
- UniProt
- P50148
- Pathways
- JAK-STAT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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