Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

KRT14 antibody (C-Term)

KRT14 Reactivity: Human IF, FACS, IHC (f) Host: Mouse Monoclonal LL002 unconjugated
Catalog No. ABIN6937656
  • Target See all KRT14 Antibodies
    KRT14 (Keratin 14 (KRT14))
    Binding Specificity
    • 21
    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 89
    • 59
    • 45
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 64
    • 29
    • 1
    Mouse
    Clonality
    • 54
    • 40
    Monoclonal
    Conjugate
    • 52
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRT14 antibody is un-conjugated
    Application
    • 35
    • 28
    • 23
    • 22
    • 21
    • 13
    • 13
    • 13
    • 11
    • 10
    • 7
    • 4
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
    Cross-Reactivity (Details)
    Human. Mouse. Rat.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
    Clone
    LL002
    Isotype
    IgG3 kappa
    Top Product
    Discover our top product KRT14 Primary Antibody
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, A549 or A431 cells. Skin or Squamous cell carcinoma.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    KRT14 (Keratin 14 (KRT14))
    Alternative Name
    KRT14 (KRT14 Products)
    Synonyms
    CK14 antibody, EBS3 antibody, EBS4 antibody, K14 antibody, NFJ antibody, AI626930 antibody, Krt-1.14 antibody, Krt1-14 antibody, Ka14 antibody, ouro2 antibody, keratin 14 antibody, keratin 14, type I L homeolog antibody, KRT14 antibody, Krt14 antibody, krt14.L antibody
    Background
    CK-14, Dowling Meara, ebs3, ebs4, Epidermolysis Bullosa Simplex, k14, Keratin 14, Keratin Type I Cytoskeletal 14, Koebner, krt14, NFJ,Cytokeratin 14 (KRT14) (Squamous Cell Marker)
    Cellular localisation: Cytoplasmic
    Molecular Weight
    50kDa
    Gene ID
    3861, 6545380
    UniProt
    P02533
You are here:
Support