MFGE8 antibody

Catalog No. ABIN6937837

Product Details anti-MFGE8 Antibody

Target: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MFGE8 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: Recognizes a protein of 40-45 kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Human milk fat globule membrane preparation

Clone: MFG-06

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Normal breast or breast carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for MFGE8

Target: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Alternative Name: MFGE8 (MFGE8 Products)

Synonyms: BA46 antibody, EDIL1 antibody, HMFG antibody, HsT19888 antibody, MFG-E8 antibody, MFGM antibody, OAcGD3S antibody, SED1 antibody, SPAG10 antibody, hP47 antibody, ba46 antibody, edil1 antibody, oacgd3s antibody, MGC75581 antibody, hst19888 antibody, MGC145109 antibody, MFGE8 antibody, mfge8 antibody, zgc:154157 antibody, MGC99228 antibody, AA408458 antibody, AI325141 antibody, Mfgm antibody, P47 antibody, lactadherin antibody, AGS antibody, MFGME8 antibody, MFGMP-E8 antibody, im:6895406 antibody, mfge8l antibody, zgc:110846 antibody, milk fat globule-EGF factor 8 protein antibody, milk fat globule-EGF factor 8 protein b antibody, milk fat globule-EGF factor 8 protein L homeolog antibody, milk fat globule-EGF factor 8 protein a antibody, MFGE8 antibody, mfge8 antibody, mfge8b antibody, mfge8.L antibody, Mfge8 antibody, mfge8a antibody

Background: Breast epithelial antigen BA46, EDIL1, HMFG, Lactadherin, Lactadherin precursor, Medin, MFGE8, MFGM, Milk fat globule-EGF factor 8 (MFG-E8),Milk Fat Globule (Breast Epithelial Marker)
Cellular localisation: Cell Surface & Cytoplasmic

Molecular Weight: 45kDa

Gene ID: 4240, 3745

UniProt: Q08431

Pathways: SARS-CoV-2 Protein Interactome