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Recombinant NEFL antibody

NEFL Reactivity: Human IHC (f) Host: Rabbit Monoclonal NEFL-2983R unconjugated Recombinant Antibody
Catalog No. ABIN6938042
  • Target See all NEFL Antibodies
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 73
    • 51
    • 39
    • 26
    • 24
    • 18
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 57
    • 35
    • 8
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 62
    • 41
    Monoclonal
    Conjugate
    • 64
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFL antibody is un-conjugated
    Application
    • 58
    • 40
    • 32
    • 23
    • 17
    • 16
    • 14
    • 14
    • 13
    • 11
    • 10
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
    Cross-Reactivity (Details)
    Human. Rat. Pig. Cow. Chicken. Dog
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human NEFL protein
    Clone
    NEFL-2983R
    Isotype
    IgG
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    Discover our top product NEFL Primary Antibody
  • Application Notes

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Brain, Neuroblastoma.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Alternative Name
    NEFL (NEFL Products)
    Synonyms
    NEFL antibody, nefl antibody, zgc:136626 antibody, AI847934 antibody, CMT2E antibody, NF-L antibody, NF68 antibody, Nfl antibody, CMT1F antibody, NFL antibody, XNF-L antibody, neurofilament light antibody, neurofilament, light polypeptide antibody, neurofilament, light polypeptide b antibody, neurofilament, light L homeolog antibody, NEFL antibody, neflb antibody, Nefl antibody, nefl.L antibody
    Background
    68 kDa neurofilament protein, Light molecular weight neurofilament protein, NEFL, Neurofilament light polypeptide 68 kDa, Neurofilament light polypeptide, Neurofilament protein, light chain, Neurofilament subunit NF-L, Neurofilament triplet L protein, NF-L, NF68,Neurofilament (NF-L) (Neuronal Marker)
    Cellular localisation: Cytoplasmic
    Molecular Weight
    68kDa
    Gene ID
    4747, 521461
    UniProt
    P07196
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