SULT1E1 antibody
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- Target See all SULT1E1 Antibodies
- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SULT1E1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human SULT1E1 protein
- Clone
- CPTC-SULT1E1-1
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product SULT1E1 Primary Antibody
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- Application Notes
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Liver tissue lysates. Human liver, intestine or kidney.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
- Alternative Name
- SULT1E1 (SULT1E1 Products)
- Synonyms
- STE antibody, St1 antibody, EST antibody, ST1E1 antibody, Ste antibody, EST-1 antibody, est-1 antibody, ste antibody, sult1e1 antibody, sult1e1.S antibody, sulfotransferase family 1E member 1 antibody, sulfotransferase family 1E, estrogen-preferring, member 1 antibody, estrogen sulfotransferase antibody, sulfotransferase family 1E, member 1 antibody, sulfotransferase family 1E member 1 L homeolog antibody, Sult1e1 antibody, SULT1E1 antibody, St1 antibody, CpipJ_CPIJ012993 antibody, CpipJ_CPIJ014515 antibody, LOC482182 antibody, sult1e1.L antibody
- Background
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EST, EST-1,EST1, Estrogen sulfotransferase, estrogen-preferring, estrone sulfotransferase, ST1E1, STE, Sulfotransferase 1E1, Sulfotransferase , Sulfotransferase estrogen preferring,Sulfotransferase family 1E, estrogen-preferring, member 1
Cellular localisation: Cytoplasm - Molecular Weight
- 35kDa
- Gene ID
- 6783, 479898
- UniProt
- P49888
- Pathways
- Steroid Hormone Biosynthesis
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