Recombinant SOX9 antibody

Catalog No. ABIN6935478

Product Details anti-SOX9 Antibody

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SOX9 antibody is un-conjugated

Application: ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogen: Recombinant human full-length SOX9 protein

Clone: SOX9-2287R

Isotype: IgG

Application Details

Application Notes:

Positive Control: Human Skin Hair follicles.

Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Alternative Name: SOX9 (SOX9 Products)

Synonyms: CMD1 antibody, CMPD1 antibody, SRA1 antibody, LOC100227849 antibody, 2010306G03Rik antibody, AV220920 antibody, mKIAA4243 antibody, SOX-9 antibody, cmd1 antibody, cmpd1 antibody, sox-9 antibody, sox9 antibody, sox9-a antibody, sox9-b antibody, sox9b antibody, sra1 antibody, SRY-box 9 antibody, transcription factor SOX-9 antibody, SRY (sex determining region Y)-box 9 antibody, SRY box 9 antibody, SRY-box 9 L homeolog antibody, SOX9 antibody, LOC100227849 antibody, Sox9 antibody, sox9.L antibody

Background: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) [MIM:114290]: Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common.

Molecular Weight: 56kDa

Gene ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development