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CD34 antibody

CD34 Reactivity: Human, Rat FACS, IF, ELISA, Coat Host: Mouse Monoclonal ICO-115 unconjugated
Catalog No. ABIN6935797
  • Target See all CD34 Antibodies
    CD34
    Reactivity
    • 294
    • 105
    • 103
    • 33
    • 19
    • 17
    • 17
    • 17
    • 16
    • 16
    • 9
    • 6
    • 6
    • 1
    • 1
    Human, Rat
    Host
    • 166
    • 142
    • 16
    • 4
    Mouse
    Clonality
    • 209
    • 116
    • 2
    Monoclonal
    Conjugate
    • 122
    • 27
    • 24
    • 20
    • 14
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD34 antibody is un-conjugated
    Application
    • 231
    • 197
    • 88
    • 64
    • 58
    • 49
    • 39
    • 37
    • 28
    • 28
    • 23
    • 18
    • 13
    • 7
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    • 3
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    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)
    Specificity
    This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85 % of angiosarcoma and Kaposi's sarcoma, but shows low specificity.
    Purification
    Purified by Protein A/G
    Immunogen
    Blast cells of a chronic myeloid leukemia patient
    Clone
    ICO-115
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD34 Primary Antibody
  • Application Notes

    Positive Control: KG-1 cells. Human tonsil or angiosarcoma.

    Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    CD34
    Alternative Name
    CD34 (CD34 Products)
    Synonyms
    AU040960 antibody, CD34 molecule antibody, CD34 antigen antibody, CD34 antibody, Cd34 antibody
    Molecular Weight
    90-110kDa
    Gene ID
    947
    UniProt
    P28906
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