EGR2 antibody
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- Target See all EGR2 Antibodies
- EGR2 (Early Growth Response 2 (EGR2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This EGR2 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant protein within human EGR2 aa 1-200.
- Clone
- 5C5
- Isotype
- IgG
- Top Product
- Discover our top product EGR2 Primary Antibody
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- Application Notes
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WB 1:300-5000
FCM 1:20-100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EGR2 (Early Growth Response 2 (EGR2))
- Alternative Name
- EGR2 (EGR2 Products)
- Synonyms
- AT591 antibody, CMT1D antibody, CMT4E antibody, KROX20 antibody, Egr-2 antibody, Krox-20 antibody, Krox20 antibody, NGF1-B antibody, Zfp-25 antibody, Zfp-6 antibody, KRX-20 antibody, cb427 antibody, egr2 antibody, id:ibd5073 antibody, krox20 antibody, krx20 antibody, wu:fb71h10 antibody, zgc:92210 antibody, frb35 antibody, early growth response 2 antibody, early growth response 2b antibody, early growth response 2a antibody, EGR2 antibody, Egr2 antibody, egr2b antibody, egr2a antibody
- Background
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Synonyms: E3 SUMO-protein ligase EGR2, AT591, E3 SUMO-protein transferase ERG2, Early growth response protein 2, Zinc finger protein Krox-20, EGR-2, EGR2, KROX20
Background: The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.
- UniProt
- P11161
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