NDUFA13 antibody

Catalog No. ABIN6944230

Product Details anti-NDUFA13 Antibody

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human GRIM19 aa 1-150.

Clone: 4F12

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: NDUFA13 (NDUFA13 Products)

Synonyms: GRIM-19 antibody, Ndufa13 antibody, B16.6 antibody, CDA016 antibody, GRIM19 antibody, 2700054G14Rik antibody, AU022060 antibody, CGI-39 antibody, Grim19 antibody, RGD1565358 antibody, YJEFN3 antibody, NADH:ubiquinone oxidoreductase subunit A13 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antibody, cell death-regulatory protein GRIM19 antibody, GRIM-19 protein antibody, NADH:ubiquinone oxidoreductase subunit A13 L homeolog antibody, ndufa13 antibody, LOC655421 antibody, Ndufa13 antibody, CpipJ_CPIJ000908 antibody, Bm1_18845 antibody, ndufa13.L antibody, NDUFA13 antibody

Background:

Synonyms: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, Cell death regulatory protein GRIM-19, Complex I-B16.6, Gene associated with retinoic and interferon-induced mortality 19 protein, NADH-ubiquinone oxidoreductase B16.6 subunit, CI-B16.6, GRIM-19, Gene associated with retinoic and IFN-induced mortality 19 protein, NDUFA13, GRIM19

Background: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes

Gene ID: 51079

UniProt: Q9P0J0

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling