MGEA5 antibody
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- Target See all MGEA5 Antibodies
- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This MGEA5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant protein of N-terminal human MGEA5.
- Clone
- 1A5
- Isotype
- IgG
- Top Product
- Discover our top product MGEA5 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IP(1-2 μg) - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
- Alternative Name
- OGA (MGEA5 Products)
- Synonyms
- MEA5 antibody, NCOAT antibody, OGA antibody, 2810009A20Rik antibody, 4833427O07Rik antibody, 5830447M11Rik antibody, AA408215 antibody, Hy5 antibody, Ncoat antibody, mKIAA0679 antibody, O-GLCNACASE antibody, cytochrome c oxidase subunit VIc antibody, meningioma expressed antigen 5 (hyaluronidase) antibody, COX6C antibody, MGEA5 antibody, Mgea5 antibody
- Background
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Synonyms: Protein O-GlcNAcase, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Meningioma-expressed antigen 5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, OGA, NCOAT, MGEA5, HEXC, KIAA0679, MEA5
Background: Isoform 1: - Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity. Isoform 3: - Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1.
- Gene ID
- 10724
- UniProt
- O60502
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
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