STIP1 antibody

Catalog No. ABIN6945069

Product Details anti-STIP1 Antibody

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein orresponding to human STIP1 aa 1-150

Clone: 2H5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STIP1

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Alternative Name: STIP1 (STIP1 Products)

Synonyms: HOP antibody, IEF-SSP-3521 antibody, P60 antibody, STI1 antibody, STI1L antibody, Hop antibody, Sti1 antibody, p60 antibody, MGC53256 antibody, stip1 antibody, MGC76181 antibody, MGC82554 antibody, zgc:92133 antibody, stress induced phosphoprotein 1 antibody, stress-induced phosphoprotein 1 antibody, stress induced phosphoprotein 1 L homeolog antibody, Stress-induced-phosphoprotein 1 antibody, stress-induced-phosphoprotein 1 antibody, stress induced phosphoprotein 1 S homeolog antibody, STIP1 antibody, Stip1 antibody, stip1.L antibody, GL50803_27310 antibody, PGTG_06468 antibody, stip1 antibody, stip1.S antibody

Background:

Synonyms: Stress-induced-phosphoprotein 1, Hsc70/Hsp90-organizing protein, Renal carcinoma antigen NY-REN-11, Transformation-sensitive protein IEF SSP 3521, STI1, Hop, STIP1

Background: Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function.

Gene ID: 10963

UniProt: P31948