TLR5 antibody
-
- Target See all TLR5 Antibodies
- TLR5 (Toll-Like Receptor 5 (TLR5))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Monoclonal
-
Conjugate
- This TLR5 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- Human TLR5 aa 700-800
- Clone
- 6C1
- Isotype
- IgG
- Top Product
- Discover our top product TLR5 Primary Antibody
-
-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- TLR5 (Toll-Like Receptor 5 (TLR5))
- Alternative Name
- TLR5 (TLR5 Products)
- Synonyms
- SLEB1 antibody, TIL3 antibody, TLR-5 antibody, sleb1 antibody, til3 antibody, tlr-5 antibody, tlr5 antibody, toll like receptor 5 antibody, toll-like receptor 5 antibody, toll like receptor 5 L homeolog antibody, toll-like receptor 5b antibody, TLR5 antibody, Tlr5 antibody, tlr5.L antibody, tlr-5 antibody, tlr5b antibody
- Background
-
Synonyms: Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, TLR5
Background: Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781). Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota (PubMed:29934223). Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response (PubMed:20855887, PubMed:11489966). Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life (By similarity).
- Gene ID
- 7100
- UniProt
- O60602
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
-