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BTLA antibody (PE)

BTLA Reactivity: Mouse FACS Host: Armenian Hamster Monoclonal 6A6 PE
Catalog No. ABIN7278353
  • Target See all BTLA Antibodies
    BTLA (B and T Lymphocyte Associated (BTLA))
    Reactivity
    • 57
    • 30
    • 4
    • 2
    • 1
    • 1
    Mouse
    Host
    • 33
    • 24
    • 10
    • 2
    • 1
    • 1
    Armenian Hamster
    Clonality
    • 37
    • 32
    • 2
    Monoclonal
    Conjugate
    • 43
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BTLA antibody is conjugated to PE
    Application
    • 46
    • 43
    • 27
    • 13
    • 13
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Purification
    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
    Clone
    6A6
    Isotype
    IgG
    Top Product
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  • Application Notes
    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
    Comment

    0.2 mg/mL

    Restrictions
    For Research Use only
  • Buffer
    10  mM NaH2PO4, 150  mM NaCl, 0.09 %  Sodium azide, 0.1 % gelatin,  pH 7.2
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    2-8°C protected from light
    Expiry Date
    12 months
  • Target
    BTLA (B and T Lymphocyte Associated (BTLA))
    Alternative Name
    CD272 (BTLA Products)
    Synonyms
    BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
    Background
    The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.
    Gene ID
    208154
    UniProt
    Q3U0X8
    Pathways
    Cancer Immune Checkpoints
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