L-Selectin antibody
-
- Target See all L-Selectin (SELL) Antibodies
- L-Selectin (SELL) (Selectin L (SELL))
-
Reactivity
- Mouse
-
Host
- Rat
-
Clonality
- Monoclonal
-
Conjugate
- This L-Selectin antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunoelectron Microscopy (IEM)
- Purification
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
- Clone
- MEL-14
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product SELL Primary Antibody
-
-
- Application Notes
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
- Comment
-
0.5 mg/mL
- Restrictions
- For Research Use only
-
- Buffer
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- 2-8°C
- Expiry Date
- 12 months
-
- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Alternative Name
- CD62L (L-Selectin) (SELL Products)
- Synonyms
- CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
- Background
- The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte rolling on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
- Gene ID
- 20343
- UniProt
- P18337
-